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肺癌細胞突變「上腦」 徵狀難辨隨時延誤醫治
 

肺癌細胞突變「上腦」 徵狀難辨隨時延誤醫治

手腳麻痹、頭暈、口齒不清,這些看似是中風的病症,竟然是生癌!有臨牀腫瘤科專科醫生表示,晚期ALK肺癌患者的癌細胞可轉移至腦部,致使病人出現疑似中風的徵狀,醫學界正嘗試採用二線藥物控制腦擴散,以代替以往效用較低的一線藥物。

荃灣臨牀腫瘤科專科醫生區兆基指出,過去曾接到一名病人求助,出現抽筋、手腳無力及一些認知障礙症的症狀,病人原先以為中風,於是安排入醫院接受檢查,惟經電腦掃描後,竟發現腦內有腫瘤,其後再為他作全身檢查,才知病人患上一種ALK基因突變的肺癌,當時癌細胞已由肺部擴散至腦部。

區兆基表示,ALK肺癌患者多沒有吸煙史及相對較年輕,約有四成肺癌患者的癌細胞會轉移至腦部。在出現腦擴散的肺癌患者中,大多沒有任何肺癌病徵,患者只會感到頭痛、手腳不協調、情緒大起大落及性格轉變等,故須進行磁力共振才能確診腦擴散。

醫學界過往會先使用一線藥物治療晚期ALK肺癌,惟效果卻未如理想。幸而,現今二線藥物的療效改善,除了藥物在顱內反應比前者高出數倍外,亦能有效控制腦擴散,甚至能令腫瘤明顯縮小。

 

區兆基醫生 DR. AU SIU KIE

資料來源: 頭條日報 09-12-2016

選文來自: 香港E大夫 / 醫大夫

 

 

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