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夥多地院校合研「無氣門蟎」進化過程 中大揭蟎基因利防治過敏
 

夥多地院校合研「無氣門蟎」進化過程 中大揭蟎基因利防治過敏

蟎蟲是令人類過敏的主要源頭,逾半港人患有至少一種過敏性疾病,而兒童個案在過去數十年間更不斷飆升。中大與多地院校合作揭開「無氣門蟎」的進化過程,為「蟎過敏」的診斷和干預奠定基因組學基礎,有助加強防治蟎過敏。

蟎過敏會暈甚至致命

無氣門蟎是由家居塵蟎、倉儲蟎和寄生蟎組成的小生物群,而家居塵蟎是本港約四至六成過敏人士的主要致敏原因,中大醫學院兒科學系助理教授梁詩彥指出,蟎過敏的常見反應,包括鼻癢、打噴嚏等,若患者攝入被蟎蟲污染的食物,會出現呼吸急促、喉嚨腫脹、暈眩,甚至是致命的過敏性休克。

蟎蟲原本被認為和蜱蟲屬於同一單系,但中大醫學院生物醫學學院徐國榮帶領的研究小組,利用六個優質基因組、對無氣門蟎作比較基因組學分析,證明無氣門蟎與植物寄生蟎和土壤蟎才是屬同一單系,並清楚描繪無氣門蟎的整個進化過程,估計無氣門蟎的祖先大約在四億一千八百萬年前,從土蟎中分支出來。團隊希望能最終有助於蟎過敏的臨牀診斷和干預。

 

資料來源:巴士的報 17-06-2022

選文來自:香港E大夫/醫大夫

 

 

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